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Capacity Building for Sustainable HIV Services

Cooperative Agreements to USA, Canada, and International Nonprofit,
Health, and Faith-Based Organizations to Benefit Patients With HIV and AIDS

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Health Resources and Services Administration (HRSA)

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Cooperative agreements to USA, Canada, and International nonprofit organizations, health organizations, and community-based and faith-based organizations for services to patients with HIV and AIDS. Applicants are advised that required registrations may take several weeks to complete. The program will support countries currently receiving capacity building support (Mozambique, Botswana, India, Jamaica, Trinidad & Tobago, and Ukraine) through HRSA’s International AIDS Education and Training Centers (IAETC) program, as well as extend this work and offer additional programming to new countries.

The purpose of this cooperative agreement, funded under the U.S. President’s Emergency Plan for AIDS Relief (PEPFAR), is to enhance the quality, effectiveness, efficiency, patient-centeredness, safety, accessibility, equity, and sustainability of HIV clinical services and related non-clinical supports in identified countries with PEPFAR programs. HRSA is committed to sustainable control of the HIV/AIDS epidemic, by working with local partners and Ministries of Health to build the capacity of health care workers and health systems to produce a sustained, efficient, and responsive approach to the HIV epidemic in resource-limited countries. The program aims to build the capacity of countries to be agile and current in their response to the needs of program beneficiaries, achieve the Joint United Nations Programme on HIV/AIDS (UNAIDS) 95-95-95 targets, and sustain these efforts over time.

The goal of this program is to improve health outcomes for people living with HIV/AIDS (PLHIV) along the HIV care continuum by building sustainable health systems, including a global workforce with the right skills, mix, and distribution to respond to HIV and other population health priorities. 

The program shall focus on:

  • Comprehensive and client-centered service delivery;
  • Quality improvement to address gaps in performance and inequities;
  • Transitioning to local partners and integration of HIV services into primary health care;
  • Strengthening Human Resources for Health (HRH);
  • Interventions to address other determinants of health, such as behavioral health;
  • Data management, telemedicine and e-learning, and health informatics/system solutions to identify and track patients, monitor results and progress; and
  • Improving diagnosis, linkage, treatment, retention and viral suppression rates.

The program also provides direct technical assistance to Ministries of Health and regional and local government entities, and supports institutional capacity building. The overall objective is to achieve and/or maintain HIV epidemic control within the PEPFAR program. 

The cooperative agreement recipient’s responsibilities can be found in the NOFO on page 9. See Supporting Documents below.

Focus Areas can be found on page 12 of the NOFO.

GrantWatch ID#:

GrantWatch ID#: 194862

Estimated Total Program Funding:


Number of Grants:

Up to two cooperative agreement(s)

Estimated Size of Grant:

Up to $50,000,000 per year subject to the availability of appropriated funds and other funding sources.

Term of Contract:

Period of Performance: September 30, 2021 through September 29, 2026 (5 years)

Additional Eligibility Criteria:

Eligible applicants include domestic or foreign public or non-profit private entities, including schools of medicine, nursing, public health, management and public administration, and academic health centers, community-based organizations, faith-based organizations, and consortia consisting of such eligible organizations.

You cannot use funds under this notice for the following purposes:
- Research
- Construction
- Travel, per diem, hotel expenses, meals, conference fees, or other conference costs for any member of a foreign government’s delegation to an international conference sponsored by a multilateral organization unless approved by HRSA in writing.

Pre-proposal Conference:

Technical Assistance:
HRSA has scheduled the following technical assistance:
- Day and Date: Wednesday, March 17, 2021
- Time: 10 a.m. – 11:30 a.m. EST
- Call-In Number: 1-888-730-9136
- Participant Code: 5686097
- Weblink:
- Playback Number: 1-800-518-0081
- Passcode: 3521

Pre-Application Information:

The due date for applications under this NOFO is May 7, 2021 at 11:59 p.m. ET. HRSA suggests submitting applications to at least 3 calendar days before the deadline to allow for any unforeseen circumstances.

Ensure your and registrations and passwords are current immediately! HRSA will not approve deadline extensions for lack of registration. Registration in all systems, including and, may take up to 1 month to complete.

You must obtain a valid DUNS number, also known as the Unique Entity Identifier (UEI), and provide that number in the application. Beginning in April 2022, the *DUNS number will be replaced by the UEI, a “new, non-proprietary identifier” requested in, and assigned by, the System for Award Management (

You must also register with SAM and continue to maintain active SAM registration with current information at all times during which you have an active federal award or an application or plan under consideration by an agency (unless the applicant is an individual or federal agency that is exempted from those requirements under 2 CFR § 25.110(b) or (c), or has an exception approved by the agency under 2 CFR § 25.110(d)).

If you are chosen as a recipient, HRSA would not make an award until you have complied with all applicable DUNS (or UEI) and SAM requirements and, if you have not fully complied with the requirements by the time HRSA is ready to make an award, you may be deemed not qualified to receive an award and use that determination as the basis for making an award to another applicant.

If you have already completed registration for HRSA or another federal agency, confirm that the registration is still active and that the Authorized Organization Representative (AOR) has been approved.

Cost Sharing/Match Required: No

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Contact Information:

Before starting your grant application, please review the funding source's website listed below for updates/changes/addendums/conferences/LOIs.

Jaclyn Perlman
Project Officer, OGH/OA
Telephone: (301) 945-0836

CFDA Number:


URL for Full Text (RFP):

Geographic Focus:

USA: Alabama;   Alaska;   Arizona;   Arkansas;   California;   Colorado;   Connecticut;   Delaware;   Florida;   Georgia;   Hawaii;   Idaho;   Illinois;   Indiana;   Iowa;   Kansas;   Kentucky;   Louisiana;   Maine;   Maryland;   Massachusetts;   Michigan;   Minnesota;   Mississippi;   Missouri;   Montana;   Nebraska;   Nevada;   New Hampshire;   New Jersey;   New Mexico;   New York City;   New York;   North Carolina;   North Dakota;   Ohio;   Oklahoma;   Oregon;   Pennsylvania;   Rhode Island;   South Carolina;   South Dakota;   Tennessee;   Texas;   Utah;   Vermont;   Virginia;   Washington, DC;   Washington;   West Virginia;   Wisconsin;   Wyoming

USA Territories: American Samoa (USA)   Guam (USA)   Puerto Rico (USA)   Virgin Islands (USA)   Northern Mariana Islands (USA)

USA Compact Free Associations: The Federated States of Micronesia (USA)   Marshall Islands (USA)   Republic of Palau (USA)

Canada: Alberta;   British Columbia;   Manitoba;   New Brunswick;   Newfoundland and Labrador;   Northwest Territories;   Nova Scotia;   Nunavut;   Ontario;   Prince Edward Island;   Quebec;   Saskatchewan;   Yukon;


International country outside of the USA, Israel and Canada.

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